Origin of a Theory: Excitatory/inhibitory imbalance in the brain as a factor in autism

In 2001, Dr. John P. Hussman published a novel hypothesis in the Journal of Autism and Developmental Disorders concerning the neurological basis of autism. Drawing together findings from genetic, clinical and neurobiological lines of autism research, Hussman proposed that much of the evidence on autism to date was consistent with disruption in the balance between…